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Quorum Sensing Inhibitors of<i>Staphylococcus aureus</i>from Italian Medicinal Plants

19 Jul 2010

Abstract excerpt

Morbidity and mortality estimates due to methicillin-resistant Staphylococcus aureus (MRSA) infections continue to rise. Therapeutic options are limited by antibiotic resistance. Anti-pathogenic compounds, which inhibit quorum sensing (QS) pathways, may be a useful alternative to antibiotics. Staphylococcal QS is encoded by the AGR locus and is responsible for the production of δ-hemolysin. Quantification of...

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PMID: 20645243
DOI: 10.1055/s-0030-1250145

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