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Identifying the essential genes of <i>Mycobacterium avium</i> subsp. <i>hominissuis</i> with Tn-Seq using a rank-based filter procedure

2019-07-19

Abstract excerpt

Mycobacterium avium (Mav) is increasingly recognized as a significant cause of morbidity, particularly in elderly patients or those with immune deficiency or underlying structural lung disease. Generally, Mav infection is treated with 2-3 antimicrobial drugs for at least 12 months. Identification of genes essential for Mav growth may yield novel strategies for improving curative therapy. We have generated saturati...

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Literature Corpus work
a0343165-a1a3-57e2-8fcb-1af0c7332064
DOI
10.1101/708495
Open publication

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