Article

Genetic determinants of intrinsic antibiotic tolerance in <i>Mycobacterium avium</i>

2021-02-24

Abstract excerpt

Mycobacterium avium complex (MAC) is one of the most prevalent causes of nontuberculous mycobacteria pulmonary infection in the United States, yet it remains understudied. Current MAC treatment requires more than a year of intermittent to daily combination antibiotic therapy, depending on disease severity. In order to shorten and simplify curative regimens, it is important to identify the innate bacterial factors...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7cea94a0-12a8-5403-ab0c-25a16c88440e
DOI: 10.1101/2021.02.23.432616

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genetic determinants of intrinsic antibiotic tolerance in <i>Mycobacterium avium</i>DOI 10.1101/2021.02.23.432616Read

Mechanisms of Antibiotic Tolerance in Mycobacterium avium Complex: Lessons From Related MycobacteriaSemantic proximity Read

Identifying the essential genes of <i>Mycobacterium avium</i> subsp. <i>hominissuis</i> with Tn-Seq using a rank-based filter procedureSemantic proximity Read

Mycobacterium avium: Diversity, Clinical Significance, Old and New Targeted Medicines.Semantic proximity Read

Rapid Emergence of Resistance to Broad-Spectrum Direct Antimicrobial Activity of AvibactamSemantic proximity Read

Molecular Mechanisms Underlying Antimicrobial Resistance in Mycobacteria.Semantic proximity Read

Genome-Wide Essentiality Analysis of Mycobacterium abscessus by Saturated Transposon Mutagenesis and Deep SequencingSemantic proximity Read

Mycobacterium abscessus Genetic Determinants Associated with the Intrinsic Resistance to AntibioticsSemantic proximity Read

Global assessment of <i>Mycobacterium avium</i> subspecies <i>hominissuis</i> genetic requirement for growth and virulenceSemantic proximity Read

Mutations in the <i>ubiA</i> gene are the major mechanism of ethambutol resistance in <i>Mycobacterium avium</i>Semantic proximity Read

Identification of Mycobacterium avium genes associated with resistance to host antimicrobial peptides.Semantic proximity Read

Functional genomics reveals strain-specific genetic requirements conferring hypoxic growth in <i>Mycobacterium intracellulare</i>Semantic proximity Read

Mycobacterium abscessus: a new antibiotic nightmareSemantic proximity Read