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Global Assessment of Mycobacterium avium subsp. hominissuis Genetic Requirement for Growth and Virulence

9 Dec 2019

Abstract excerpt

Pulmonary disease caused by nontuberculous mycobacteria is increasing worldwide. The majority of these infections are caused by the Mycobacterium avium complex (MAC), whereof >90% are due to Mycobacterium avium subsp. hominissuis (MAH). Treatment of MAH infections is currently difficult, with a combination of antibiotics given for at least 12 months. To control MAH by improved therapy, prevention, and...

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PMID: 31822597
DOI: 10.1128/msystems.00402-19

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