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Functional genomics reveals strain-specific genetic requirements conferring hypoxic growth in <i>Mycobacterium intracellulare</i>

2024-05-13

Abstract excerpt

Mycobacterium intracellulare is a major etiological agent of the recently expanding Mycobacterium avium–intracellulare complex pulmonary disease (MAC-PD). Therapeutic regimens that include a combination of macrolides and antituberculous drugs have been implemented with limited success. To identify novel targets for drug development that accommodate the genomic diversity of M. avium–intracellulare , we subjected...

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Literature Corpus work
98e9f482-8b17-51bd-97e6-c24868e877d3
DOI
10.1101/2024.05.12.593797
Open publication

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Functional genomics reveals strain-specific genetic requirements conferring hypoxic growth in <i>Mycobacterium intracellulare</i>DOI 10.1101/2024.05.12.593797
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