Article

Bax Forms a Membrane Surface Protein-Lipid Complex as it Initiates Apoptosis

2022-11-02

Abstract excerpt

Cellular clearance by apoptosis is essential in life. In its intrinsic (mitochondrial) pathway apoptotic members of the Bcl-2 (B cell CLL/lymphoma-2) protein family, such as Bax (Bcl-2-associated X) protein, perforate the mitochondrial outer membrane (MOM), which causes release of apoptotic factors and final cell death. How those apoptotic proteins mechanistically exert their action at the membrane level still how...

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Literature Corpus work: a02141ed-abcf-5008-ad32-5e9ab74972cf
DOI: 10.1101/2022.11.01.514672

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