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Article

Transmembrane pore formation by the carboxyl terminus of Bax protein.

Biochimica et biophysica acta - 1 Feb 2013

Garg Pranav, Nemec Kathleen N, Khaled Annette R, Tatulian Suren A

Abstract excerpt

Bax is a cytosolic protein that responds to various apoptotic signals by binding to the outer mitochondrial membrane, resulting in membrane permeabilization, release of cytochrome c, and caspase-mediated cell death. Currently discussed mechanisms of membrane perforation include formation of hetero-oligomeric complexes of Bax with other pro-apoptotic proteins such as Bak, or membrane insertion of multiple...

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Identifiers

PMID: 22906710
DOI: 10.1016/j.bbamem.2012.08.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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