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Article

BAX inhibitor‐1: between stress and survival

16 Dec 2019

Abstract excerpt

Cellular gatekeepers are essential to maintain order within a cell and anticipate signals of stress to promote survival. BCL2 associated X, apoptosis regulator (BAX) inhibitor-1 (BI-1), also named transmembrane BAX inhibitor motif containing-6, is a highly conserved endoplasmic reticulum (ER) transmembrane protein. Originally identified as an inhibitor of BAX-induced apoptosis, its pro-survival properties have...

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PMID: 31841271
DOI: 10.1111/febs.15179

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