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GRAFTS OF EMBRYONIC A9 DOPAMINE NEURONS IN A RAT ORGANOTYPIC CULTURE MODEL OF PARKINSON'S DISEASE INDICATES THE POTENTIAL AND LIMITS OF NIGRO-STRIATAL CIRCUITRY REFORMATION

2025-11-07

Abstract excerpt

Primary dopaminergic cell transplantation is a potential therapeutic strategy for Parkinson’s disease. However, the procedure commonly involves placing donor neurons heterotopically into the host striatum. To gain insights into the potential to reform circuitry between the substantia nigra and striatum, a sagittal explant system, including the striatum, medial forebrain bundle (MFB) and ventral mesencephalon (VM),...

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Literature Corpus work
a01ab001-a931-5353-832d-01f1b5b71e33
DOI
10.22541/au.176249368.84343363/v1
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GRAFTS OF EMBRYONIC A9 DOPAMINE NEURONS IN A RAT ORGANOTYPIC CULTURE MODEL OF PARKINSON'S DISEASE INDICATES THE POTENTIAL AND LIMITS OF NIGRO-STRIATAL CIRCUITRY REFORMATIONDOI 10.22541/au.176249368.84343363/v1
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