Article
Exogenous erythropoietin provides neuroprotection of grafted dopamine neurons in a rodent model of Parkinson's disease.
Brain research - 12 Jan 2006
Kanaan Nicholas M, Collier Timothy J, Marchionini Deanna M, McGuire Susan O, Fleming Matthew F, Sortwell Caryl E
Abstract excerpt
Parkinson's disease (PD) is a neurodegenerative disease marked by severe loss of dopamine (DA) neurons in the nigrostriatal system, which results in depletion of striatal DA. Transplantation of embryonic ventral mesencephalic (VM) DA neurons into the striatum is a currently explored experimental treatment aimed at replacing lost DA in the nigrostriatal system, but is plagued with poor survival (5-20%) of...
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