Article

Mechanisms of piRNA biogenesis and co-transcriptional silencing of transposable elements in Drosophila

2020-01-01

Abstract excerpt

A large fraction of eukaryotic genomes consists of mobile, repetitive elements called transposons. Since their uncontrolled mobilisation is a potentially harmful event, several molecular mechanisms have evolved to counteract transposon activation and thus safeguard genome integrity. Among these is the piRNA pathway, a gonad-specific system based on small non-coding RNAs that recognise active transposons and instru...

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Literature Corpus work: b1b1d972-3062-531e-afb9-b945c64c64c5
DOI: 10.17863/cam.55019

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