Article

CXXC-finger protein 1 associates with FOXP3 to stabilize homeostasis and suppressive functions of regulatory T cells

2024-10-01

Abstract excerpt

FOXP3-expressing regulatory T (T reg ) cells play a pivotal role in maintaining immune homeostasis and tolerance, with their activation being crucial for preventing various inflammatory responses. However, the mechanisms governing the epigenetic program in T reg cells during their dynamic activation remain unclear. In this study, we demonstrate that CXXC finger protein 1 (CXXC1) interacts with the transcription...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9fe24dd0-f787-5a94-9233-a41f8673f1b7
DOI: 10.1101/2024.09.30.615805

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

CXXC-finger protein 1 associates with FOXP3 to stabilize homeostasis and suppressive functions of regulatory T cellsDOI 10.1101/2024.09.30.615805Read

Molecular feature and therapeutic perspectives of immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome.Semantic proximity Read

FOXP3: genetic and epigenetic implications for autoimmunity.Semantic proximity Read

Foxp3 in the Immune SystemSemantic proximity Read

Ikzf1 association with Foxp3 for Foxp3-dependent gene repression in Treg cells: induction of autoimmunity and tumor immunity by disrupting the associationSemantic proximity Read

Regulatory T cells and Foxp3.Semantic proximity Read

Genomics of FOXP3 Enhance Treg and Maintain Immune-homeostasisSemantic proximity Read

Forkhead box P3: the peacekeeper of the immune system.Semantic proximity Read

Epigenetic mechanisms of regulation of Foxp3 expression.Semantic proximity Read

Post-Translational Regulations of Foxp3 in Treg Cells and Their Therapeutic Applications.Semantic proximity Read

Transcriptional control of regulatory T-cell differentiation.Semantic proximity Read

Foxo proteins cooperatively control the differentiation of Foxp3+ regulatory T cells.Semantic proximity Read

FOXP3 orchestrates H4K16 acetylation and H3K4 trimethylation for activation of multiple genes by recruiting MOF and causing displacement of PLU-1.Semantic proximity Read