Article

Drug mechanism enrichment analysis improves prioritization of therapeutics for repurposing

2022-03-18

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> There is a pressing need for improved methods to identify effective therapeutics for disease. Many computational approaches have been developed to repurpose existing drugs to meet this need. However, these tools often output long lists of candidate drugs that are difficult to interpret, and individual drug candidates may suffer from unknown off-target effects. We reasoned th...

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Literature Corpus work: 9fd0c015-75d4-5393-b216-2a39f4f44cb3
DOI: 10.1101/2022.03.15.484520

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