Article

Prioritization of Potential Drugs Through Pathway-Based Drug Repurposing and Network Proximity Analysis

2025-06-08

Abstract excerpt

Drug repurposing is an effective strategy to identify novel therapeutic options by leveraging existing drugs with known mechanisms of action and safety profiles. This work introduces a pathway-based drug repurposing approach that combines protein-protein interaction (PPI) networks and transcriptomic data to prioritize candidate drugs. The underlying assumption is that if disease 1 and disease 2 are both associated...

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Literature Corpus work: 43eda6b6-4aba-596b-b26a-50e34c2ebde7
DOI: 10.1101/2025.06.05.658004

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