Article

SenolyticSynergy: An Attention-Based Network for Discovering Novel Senolytic Combinations via Human Aging Genomics

2025-05-30

Abstract excerpt

<h4>ABSTRACT</h4> Senolytics, a category of drugs targeting aging processes, have garnered significant attention since their emergence in 2015. Unlike traditional drug development approaches that rely on randomized screening, research on aging-related pharmaceuticals has employed mechanism-based strategies, resulting in the discovery of the pioneering combination therapy of dasatinib (D) and quercetin (Q). Althou...

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Literature Corpus work: a9f379e4-5ff6-5ad4-93cd-ddb86f7e6413
DOI: 10.1101/2025.05.28.655258

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