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Article

Drug-set enrichment analysis: a novel tool to investigate drug mode of action.

Bioinformatics (Oxford, England) - 15 Jan 2016

Napolitano Francesco, Sirci Francesco, Carrella Diego, di Bernardo Diego

Abstract excerpt

MOTIVATION: Automated screening approaches are able to rapidly identify a set of small molecules inducing a desired phenotype from large small-molecule libraries. However, the resulting set of candidate molecules is usually very diverse pharmacologically, thus little insight on the shared mechanism of action (MoA) underlying their efficacy can be gained. RESULTS: We introduce a computational method (Drug-Set...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26415724
DOI: 10.1093/bioinformatics/btv536
PMCID: PMC4795590

Genes

CFTR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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