Article

TranSynergy: Mechanism-Driven Interpretable Deep Neural Network for the Synergistic Prediction and Pathway Deconvolution of Drug Combinations

2020-07-10

Abstract excerpt

<h4>Motivation</h4> Drug combinations have demonstrated great potential in cancer treatments. They alleviate drug resistance and improve therapeutic efficacy. With the fast-growing number of anti-cancer drugs, the experimental investigation of all drug combinations is costly and time-consuming. Computational techniques can improve the efficiency of drug combination screening. Despite recent advances in applying m...

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Literature Corpus work: 2e9b1861-e2e9-542b-9ed9-04a5284d6901
DOI: 10.1101/2020.07.08.193904

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