Back to search

Article

Network-based estimation of therapeutic efficacy and adverse reaction potential for prioritisation of anti-cancer drug combinations

2024-09-18

Abstract excerpt

<h4>ABSTRACT</h4> Drug combinations, although a key therapeutic agent against cancer, are yet to reach their full applicability potential due to the challenges involved in the identification of effective and safe drug pairs. In vitro or in vivo screening would have been the optimal approach if combinatorial explosion was not an issue. In silico methods, on the other hand, can enable rapid screening of drug pai...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
69d2a811-698d-5ad8-9788-727cc0d83428
DOI
10.1101/2024.09.17.613439
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Network-based estimation of therapeutic efficacy and adverse reaction potential for prioritisation of anti-cancer drug combinationsDOI 10.1101/2024.09.17.613439
Select a neighboring publication to make it the new centre.