Article

ORFhunteR: an accurate approach for the automatic identification and annotation of open reading frames in human mRNA molecules

2021-02-08

Abstract excerpt

<h4>Motivation</h4> Modern methods of whole transcriptome sequencing accurately recover nucleotide sequences of RNA molecules present in cells and allow for determining their quantitative abundances. The coding potential of such molecules can be estimated using open reading frames (ORF) finding algorithms, implemented in a number of software packages. However, these algorithms show somewhat limited accuracy, are...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cc60c345-0f4c-569c-bd5a-7c1d08660765
DOI: 10.1101/2021.02.05.429963

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

ORFhunteR: an accurate approach for the automatic identification and annotation of open reading frames in human mRNA moleculesDOI 10.1101/2021.02.05.429963Read

A community-driven roadmap to advance research on translated open reading frames detected by Ribo-seqSemantic proximity Read

A comprehensive catalog of predicted functional upstream open reading frames in humans.Semantic proximity Read

<i>uORF-Tools</i> – Workflow for the determination of translation-regulatory upstream open reading framesSemantic proximity Read

An expanded reference catalog of translated open reading frames for biomedical researchSemantic proximity Read

RNAsamba: coding potential assessment using ORF and whole transcript sequence informationSemantic proximity Read

What can Ribo-seq and proteomics tell us about the non-canonical proteome?Semantic proximity Read

Investigating Open Reading Frames in Known and Novel Transcripts using ORFanageSemantic proximity Read

MetamORF: A repository of unique short Open Reading Frames identified by both experimental and computational approaches for gene-level and meta-analysisSemantic proximity Read

Upstream open reading frames may contain hundreds of novel human exonsSemantic proximity Read

Use of short-read RNA-Seq data to identify transcripts that can translate novel ORFsSemantic proximity Read

ORF Capture-Seq: a versatile method for targeted identification of full-length isoformsSemantic proximity Read

Analysis of human upstream open reading frames and impact on gene expression.Semantic proximity Read