Article

Pervasive compartment-specific regulation of gene expression during homeostatic synaptic scaling

2020-08-31

Abstract excerpt

Synaptic scaling is a form of homeostatic plasticity which allows neurons to adjust their action potential firing rate in response to chronic alterations in neural activity. Synaptic scaling requires profound changes in gene expression, but the relative contribution of local and cell-wide mechanisms is controversial. Here we performed a comprehensive multi-omics characterization of the somatic and process compartm...

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Literature Corpus work: 9fa9013a-6b7f-56a0-a1e6-f82c850a3b22
DOI: 10.1101/2020.08.31.274993

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