Article

RAI1 Regulates Activity-Dependent Nascent Transcription and Synaptic Scaling

2019-01-18

Abstract excerpt

Long-lasting forms of synaptic plasticity such as synaptic scaling are critically dependent on transcription. Activity-dependent transcriptional dynamics in neurons, however, have not been fully characterized, because most previous efforts relied on measurement of steady-state mRNAs. Here, we profiled transcriptional dynamics of primary neuronal cultures undergoing network activity shifts using nascent RNA sequenc...

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Literature Corpus work: 7afe1244-126f-5601-a97b-8bae1cf40c09
DOI: 10.1101/523456

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