Article

Cytoskeletal and integrin-mediated mechanobiology of the alveolar epithelium

2018-01-01

Abstract excerpt

Ventilator-associated lung injury (VALI) describes the process by which mechanical ventilation of the lungs causes systemic injury. Cyclic Mechanical Strain (CMS) of alveolar epithelial cells induces cytokine release, suggesting that mechanotransduction of force into injurious biological signaling occurs in the alveolar epithelium. The work in this thesis investigated the role of integrin and cytoskeletal signalli...

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Literature Corpus work: 9f7152b4-5e07-5ec8-9abc-fe72b214c3da
DOI: 10.25560/56646

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