MicroRNA modulate alveolar epithelial response to cyclic stretch

Abstract excerpt

BACKGROUND: MicroRNAs (miRNAs) are post-transcriptional regulators of gene expression implicated in multiple cellular processes. Cyclic stretch of alveoli is characteristic of mechanical ventilation, and is postulated to be partly responsible for the lung injury and inflammation in ventilator-induced lung injury. We propose that miRNAs may regulate some of the stretch response, and therefore hypothesized that...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Inhalation and Respiratory Drug Delivery
• Share to MicroRNA in disease regulation
• Share to Respiratory Support and Mechanisms