Article
Equibiaxial deformation-induced injury of alveolar epithelial cells in vitro.
The American journal of physiology - 1 Dec 1998
Tschumperlin D J, Margulies S S
Abstract excerpt
Deformation of the alveolar epithelial basement membrane with lung inflation has been implicated in blood-gas barrier breakdown during the development of ventilator-induced lung injury. To determine the vulnerability of alveolar epithelial cells to deformation-induced injury, we developed a cell-stretching device that subjects cells to cyclic, equibiaxial strains. Alveolar epithelial type II cells from primary...
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