Article

Quantitative trait loci mapping of gene expression and chromatin accessibility in primary fibroblast reveals shared allelic effects between Latin American and European ancestries

2025-06-10

Abstract excerpt

<h4>ABSTRACT</h4> Quantitative Trait Locus (QTL) analysis of molecular data has identified genetic variants associated with traits such as gene expression, and colocalization of these functional QTL with GWAS risk loci has offered insights into the genetic basis of human disease. We employed gene expression (RNA-seq) and chromatin accessibility (ATAC-seq) obtained from human primary fibroblasts to investigate qua...

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Literature Corpus work: 9f26f82c-b04a-568a-935a-3931487a448b
DOI: 10.1101/2025.06.09.658613

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