Article
Sources of gene expression variation in a globally diverse human cohort.
Nature - 1 Aug 2024
Taylor Dylan J, Chhetri Surya B, Tassia Michael G, Biddanda Arjun, Yan Stephanie M, Wojcik Genevieve L, Battle Alexis, McCoy Rajiv C
Abstract excerpt
Genetic variation that influences gene expression and splicing is a key source of phenotypic diversity1-5. Although invaluable, studies investigating these links in humans have been strongly biased towards participants of European ancestries, which constrains generalizability and hinders evolutionary research. Here to address these limitations, we developed MAGE, an open-access RNA sequencing dataset of...
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