Article

Fine-mapping <i>cis</i> -regulatory variants in diverse human populations

2018-08-03

Abstract excerpt

Genome-wide association studies (GWAS) are a powerful approach for connecting genotype to phenotype. Most GWAS hits are located in cis-regulatory regions, but the underlying causal variants and their molecular mechanisms remain unknown. To better understand human cis -regulatory variation, we mapped quantitative trait loci for chromatin accessibility (caQTLs)—a key step in cis-regulation—in 1000 individuals from...

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Literature Corpus work: 4c90a9f7-3acf-587b-a270-14d9b32f5088
DOI: 10.1101/384396

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