Article

Linking Transcriptional and Cellular Responses of Human and Murine Pneumococcal Pneumonia

2025-02-13

Abstract excerpt

Community-acquired pneumonia (CAP), often caused by Streptococcus pneumoniae , poses a significant global health challenge, especially among high-risk populations. This study investigates the temporal dynamics of pulmonary gene expression during S. pneumoniae -induced pneumonia using a murine model to elucidate host-pathogen interactions and identify potential biomarkers of disease severity. Using bulk RNA seque...

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Literature Corpus work: af0a0846-9665-55fe-8754-38340eb37ce0
DOI: 10.1101/2025.02.13.638069

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