Article
Comparative transcriptional profiling of the lung reveals shared and distinct features of Streptococcus pneumoniae and influenza A virus infection.
Immunology - 1 Mar 2007
Rosseau Simone, Hocke Andreas, Mollenkopf Hans, Schmeck Bernd, Suttorp Norbert, Kaufmann Stefan H E, Zerrahn Jens
Abstract excerpt
Pneumonia is the most common cause of death from infectious disease in the western hemisphere. Pathophysiological and protective processes are initiated by pattern recognition of microbial structures. To provide the molecular framework for a better understanding of processes relevant to host defence in pneumonia, we performed pulmonary transcriptome analysis in mice infected with the major bacterial and viral...
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