Article

Ageing impairs the airway epithelium defence response to SARS-CoV-2

2021-04-06

Abstract excerpt

Age-dependent differences in the clinical response to SARS-CoV-2 infection is well-documented 1–3 however the underlying molecular mechanisms involved are poorly understood. We infected fully differentiated human nasal epithelium cultures derived from healthy children (1-12 years old), young adults (26-34 years old) and older adults (56-62 years old) with SARS-COV-2 to identify age-related cell-intrinsic differen...

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Literature Corpus work: 66676874-e55c-541b-b3b7-e42a8077d497
DOI: 10.1101/2021.04.05.437453

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