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Article

Role of isocitrate dehydrogenase in glioma.

Expert review of neurotherapeutics - 1 Oct 2011

Alexander Brian M, Mehta Minesh P

Abstract excerpt

Recently, the isocitrate dehydrogenase (IDH) enzymes have become a focal point for research aimed at understanding the biology of glioma and identifying novel targets for therapy. Following the publication of a landmark genetic sequencing study in 2008, which identified IDH1 as a frequently mutated gene in glioblastoma, much work has been carried out to further characterize the frequency, associations and...

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Source

Identifiers

PMID: 21955197
DOI: 10.1586/ern.11.134

Genes

IDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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