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Article

Integrated analysis of the genomic and transcriptional profile of gliomas with isocitrate dehydrogenase-1 and tumor protein 53 mutations.

International journal of immunopathology and pharmacology - 1 Jan 2000

Liu Han-Qing, Li Wei-Xin, An Ya-Wen, Wu Tao, Jiang Guang-Yu, Dong Yu, Chen Wei-Xin, Wang Jian-Chun, Wang Cheng, Song Shuo

Abstract excerpt

Background: The gene mutation of isocitrate dehydrogenase-1 (IDH1) is commonly found in LGG and some GBM patients and usually carries tumor protein 53 (TP53) mutations. However, the underlying mechanisms on both mutations of glioma patients in IDH1 and TP53 are still unclear. Aim: To find the potential target markers in GBM and LGG patients with IDH1 and TP53 mutation.Method: A total of 1122 glioma patients from...

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Identifiers

PMID: 36377597
DOI: 10.1177/03946320221139262
PMCID: PMC9669701

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