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Article

Isocitrate dehydrogenase 1 and 2 mutations in gliomas.

Journal of neuroscience research - 1 Dec 2014

Megova Magdalena, Drabek Jiri, Koudelakova Vladimira, Trojanec Radek, Kalita Ondrej, Hajduch Marian

Abstract excerpt

Over the past few years, new biomarkers have allowed a deeper insight into gliomagenesis and facilitated the identification of possible targets for glioma therapy. Isocitrate dehydrogenase (IDH) 1 and IDH2 mutations have been shown to be promising biomarkers for monitoring disease prognosis and predicting the response to treatment. This review summarizes recent findings in this field. Web of Science, Science...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25078896
DOI: 10.1002/jnr.23456

Genes

IDH1
IDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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