Article

IL-22 promotes genesis of small intestinal secretory cells that protect against cholera in mice

2025-09-12

Abstract excerpt

The diarrheal disease cholera remains a global threat, but there is limited knowledge of the innate immune defenses in the small intestine that protect against the causative agent, Vibrio cholerae . Here, single-cell RNA-sequencing of epithelial and immune cells mapped gene expression patterns in the infant mouse small intestine and revealed changes in response to V. cholerae infection and prophylactic treatment...

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Literature Corpus work: 9eb0e2d8-e694-51fc-90d5-c788896cd631
DOI: 10.1101/2025.09.12.675873

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