Article

Single-cell profiling of environmental enteropathy reveals signatures of epithelial remodeling and immune activation in severe disease

2021-04-12

Abstract excerpt

Environmental enteropathy (EE) is a subclinical condition of the small intestine that is highly prevalent in low- and middle-income countries. It is thought to be a key contributing factor to childhood malnutrition, growth-stunting, and diminished oral vaccine responses. While EE has been shown to be the by-product of recurrent enteric infection, its full pathophysiology remains unclear. Here, we mapped the cellul...

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Literature Corpus work: 0f8c6786-cf05-5a4c-b53a-e0afe193cb93
DOI: 10.1101/2021.04.11.439202

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