Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Frontline defenders: goblet cell mediators dictate host-microbe interactions in the intestinal tract during health and disease

8 Jan 2018

Abstract excerpt

Goblet cells (GCs) are the predominant secretory epithelial cells lining the luminal surface of the mammalian gastrointestinal (GI) tract. Best known for their apical release of mucin 2 (Muc2), which is critical for the formation of the intestinal mucus barrier, GCs have often been overlooked for their active contributions to intestinal protection and host defense. In part, this oversight reflects the limited...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gut microbiota and health
Share to Helicobacter pylori-related gastroenterology studies
Share to Infant Nutrition and Health

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29122749
DOI: 10.1152/ajpgi.00181.2017

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Frontline defenders: goblet cell mediators dictate host-microbe interactions in the intestinal tract during health and diseasePMID 29122749Read ↗

Goblet cells: guardians of gut immunity and their role in gastrointestinal diseasesSemantic proximity Read ↗

Role of Intestinal Mucins in Innate Host Defense Mechanisms against PathogensSemantic proximity Read ↗

The Front Line of Enteric Host Defense against Unwelcome Intrusion of Harmful Microorganisms: Mucins, Antimicrobial Peptides, and MicrobiotaSemantic proximity Read ↗

VAMP8-mediated MUC2 mucin exocytosis from colonic goblet cells maintains innate intestinal homeostasisSemantic proximity Read ↗

Mucins Dynamics in Physiological and Pathological ConditionsSemantic proximity Read ↗

Establishing Boundaries: The Relationship That Exists between Intestinal Epithelial Cells and Gut-Dwelling BacteriaSemantic proximity Read ↗

An intercrypt subpopulation of goblet cells is essential for colonic mucus barrier functionSemantic proximity Read ↗

Microbial sensing by goblet cells controls immune surveillance of luminal antigens in the colon.Semantic proximity Read ↗

Entamoeba histolytica -Induced Mucin Exocytosis Is Mediated by VAMP8 and Is Critical in Mucosal Innate Host DefenseSemantic proximity Read ↗

The Nlrp6 inflammasome is not required for baseline colonic inner mucus layer formation or functionSemantic proximity Read ↗

Gut γδ T cells as guardians, disruptors, and instigators of cancerSemantic proximity Read ↗

MUC17 is an essential small intestinal glycocalyx component that is disrupted in Crohn’s diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.