Article

An image-based transcriptomics atlas reveals the regional and microbiota-dependent molecular, cellular, and spatial structure of the murine gut

2025-07-24

Abstract excerpt

<h4>SUMMARY</h4> The gastrointestinal environment is home to a massive diversity of diet-, host-, and microbiota-derived small molecules, collectively sensed by a remarkable variety of cells. To explore the cellular and spatial organization of sensation, we used MERFISH to profile receptor expression across 2.1 million cells in multiple regions of the murine gut under specific-pathogen-free (SPF) and germ-free (G...

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Literature Corpus work: 8a3c76aa-c28e-59df-b286-9271fd695c17
DOI: 10.1101/2025.07.21.665958

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