Article

Single-cell RNA sequencing of intestinal immune cells in neonatal necrotizing enterocolitis

2023-01-20

Abstract excerpt

<h4>Purpose: </h4> Necrotizing enterocolitis (NEC) causes fatal intestinal necrosis in neonates, but its etiology is unknown. We analyzed the intestinal immune response to NEC. Methods Using single-cell RNA sequencing (scRNA-seq), we analyzed the gene-expression profiles of intestinal immune cells from four neonates with intestinal perforation (two with NEC and two without NEC). Target mononuclear cells were extr...

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Literature Corpus work: 9b00fb73-c1a7-5e32-9059-7aaf814f342d
DOI: 10.21203/rs.3.rs-2491577/v1

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