Article
Evidence implicating sequential commitment of the founder lineages in the human blastocyst by order of hypoblast gene activation
2022-12-10
Abstract excerpt
Successful human pregnancy depends upon rapid establishment of three founder lineages: trophectoderm, epiblast and hypoblast, which together form the blastocyst. Each plays an essential role in preparing the embryo for implantation and subsequent development. Several models are proposed to define the lineage segregation. The first suggests that all specify simultaneously; the second favours differentiation of trop...
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Identifiers and source
- Literature Corpus work
- 9ea5d4c7-236f-5102-a39a-73be7586d3ee
- DOI
- 10.1101/2022.12.08.519626