A single cell characterisation of human embryogenesis identifies pluripotency transitions and putative anterior hypoblast centre

Abstract excerpt

Following implantation, the human embryo undergoes major morphogenetic transformations that establish the future body plan. While the molecular events underpinning this process are established in mice, they remain unknown in humans. Here we characterise key events of human embryo morphogenesis, in the period between implantation and gastrulation, using single-cell analyses and functional studies. First, the...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Pluripotent Stem Cells Research
• Share to Renal and related cancers
• Share to Tissue Engineering and Regenerative Medicine