Article
Mechanism of cell polarisation and first lineage segregation in the human embryo
2020-09-23
Abstract excerpt
The formation of differential cell lineages in the mammalian blastocyst from the totipotent zygote is crucial for implantation and the success of the whole pregnancy. The first lineage segregation generates the polarised trophectoderm (TE) tissue, which forms the placenta, and the apolar inner cell mass (ICM), which mainly gives rise to all foetal tissues and also the yolk sac 1–3 . The mechanism underlying this...
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Identifiers and source
- Literature Corpus work
- c00362c8-0765-5345-ace0-37c3acdd4131
- DOI
- 10.1101/2020.09.23.310680