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Nrf2-mediated therapeutic effects of dietary flavones in different diseases

12 Sept 2023

Abstract excerpt

Oxidative stress (OS) is a pathological status that occurs when the body's balance between oxidants and antioxidant defense systems is broken, which can promote the development of many diseases. Nrf2, a redox-sensitive transcription encoded by NFE2L2, is the master regulator of phase II antioxidant enzymes and cytoprotective genes. In this context, Nrf2/ARE signaling can be a compelling target against OS-induced...

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PMID: 37767395
DOI: 10.3389/fphar.2023.1240433

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