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Article

Anti-Ferroptotic Effects of Nrf2: Beyond the Antioxidant Response

1 Mar 2023

Abstract excerpt

The transcription factor Nrf2 was originally identified as a master regulator of redox homeostasis, as it governs the expression of a battery of genes involved in mitigating oxidative and electrophilic stress. However, the central role of Nrf2 in dictating multiple facets of the cellular stress response has defined the Nrf2 pathway as a general mediator of cell survival. Recent studies have indicated that Nrf2...

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PMID: 36994475
DOI: 10.14348/molcells.2023.0005

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