Article

Chromatin state shapes site-specific A-to-I RNA editing

2026-07-27

Abstract excerpt

Adenosine-to-inosine (A-to-I) RNA editing is a widespread post-transcriptional mechanism that diversifies the transcriptome. While ADAR enzymes catalyze this reaction, the upstream mechanisms that determine why individual adenosines are edited at markedly different efficiencies remain poorly understood. Here, we integrated multi-omics datasets from human cell lines and mouse embryonic tissues and developed machine...

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Literature Corpus work: 9e4c7e6a-c227-5f8d-ad68-cf5615797ffe
DOI: 10.64898/2026.07.27.740859

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