Back to search

Article

Dystrophin modulates focal adhesion tension and YAP-mediated mechanotransduction

2021-08-06

Abstract excerpt

Dystrophin is an essential muscle protein that contributes to cell membrane stability by linking the actin cytoskeleton to the extracellular matrix. The absence or impaired function of dystrophin causes muscular dystrophy. Focal adhesions are mechanosensitive adhesion complexes that also connect the cytoskeleton to the extracellular matrix. However, the interplay between dystrophin and focal adhesion force transmi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
9e374845-fdd8-544d-99d2-67acded463a9
DOI
10.1101/2021.08.05.455167
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Dystrophin modulates focal adhesion tension and YAP-mediated mechanotransductionDOI 10.1101/2021.08.05.455167
Dystrophin missense mutations alter focal adhesion tension and mechanotransduction.Semantic proximity
Involvement of the FAK Network in Pathologies Related to Altered MechanotransductionSemantic proximity
Muscular dystrophies, the cytoskeleton and cell adhesion.Semantic proximity
Vinculin Force Sensor Detects Tumor-Osteocyte InteractionsSemantic proximity
Focal adhesion kinase-dependent regulation of adhesive forces involves vinculin recruitment to focal adhesions.Semantic proximity
Measurement systems for cell adhesive forces.Semantic proximity
Cellular microenvironments reveal defective mechanosensing responses and elevated YAP signaling in LMNA-mutated muscle precursors.Semantic proximity
A Focal Adhesion Filament Cross-correlation Kit for fast, automated segmentation and correlation of focal adhesions and actin stress fibers in cellsSemantic proximity
From Sensor Design to Force Maps: A Systematic Evaluation of FRET-based Vinculin Tension SensorsSemantic proximity
Molecular mechanism of vinculin activation and nanoscale spatial organization in focal adhesions.Semantic proximity
Reduced cell-substrate adhesion formation promotes cell migration in Dictyostelium.Semantic proximity
Dystrophin is a mechanical tension modulatorSemantic proximity
Select a neighboring publication to make it the new centre.