Article

Randomized Crossover Clinical Trial of Nicotinamide Riboside and Coenzyme Q10 on Metabolic Health and Mitochondrial Bioenergetics in CKD

2024-08-23

Abstract excerpt

<h4>Background</h4> Mitochondria-driven oxidative/redox stress and inflammation play a major role in chronic kidney disease (CKD) pathophysiology. Compounds targeting mitochondrial metabolism may improve mitochondrial function, inflammation, and redox stress; however, there is limited evidence of their efficacy in CKD. <h4>Methods</h4> We conducted a randomized, double-blind, placebo-controlled crossover trial com...

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Literature Corpus work: 9e27ae19-db72-52c9-8ba2-2d053d4b97e6
DOI: 10.1101/2024.08.23.24312501

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