Article

Nicotinamide riboside augments the human skeletal muscle NAD <sup>+</sup> metabolome and induces transcriptomic and anti-inflammatory signatures in aged subjects: a placebo-controlled, randomized trial

2019-06-28

Abstract excerpt

<h4>SUMMARY</h4> NAD + is modulated by conditions of metabolic stress and has been reported to decline with aging, but human data are sparse. Nicotinamide riboside (NR) supplementation ameliorates metabolic dysfunction in rodents. We aimed to establish whether oral NR supplementation in aged participants can increase the skeletal muscle NAD + metabolome, and questioned if tissue NAD + levels are depressed with...

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Literature Corpus work: d14301c8-1802-5e9e-bdad-53c84489167f
DOI: 10.1101/680462

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