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Article

Multiomics identifies unique modulators of calf muscle pathophysiology in peripheral artery disease and chronic kidney disease

2024-10-01

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> Chronic kidney disease (CKD) has emerged as a significant risk factor that accelerates atherosclerosis, decreases muscle function, and increases the risk of amputation or death in patients with peripheral artery disease (PAD). However, the modulators underlying this exacerbated pathobiology are ill-defined. Recent work has demonstrated that uremic toxins are associated with li...

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Literature Corpus work
f5281161-88e3-58c7-b078-4a45c9724377
DOI
10.1101/2024.09.30.24314668
Open publication

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Multiomics identifies unique modulators of calf muscle pathophysiology in peripheral artery disease and chronic kidney diseaseDOI 10.1101/2024.09.30.24314668
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