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Mitochondrial dysregulation and oxidative stress in patients with chronic kidney disease

21 Aug 2009

Abstract excerpt

BACKGROUND: Chronic renal disease (CKD) is characterized by complex changes in cell metabolism leading to an increased production of oxygen radicals, that, in turn has been suggested to play a key role in numerous clinical complications of this pathological condition. Several reports have focused on the identification of biological elements involved in the development of systemic biochemical alterations in CKD,...

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PMID: 19698090
DOI: 10.1186/1471-2164-10-388

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