Article

Ketone body mediated histone β-hydroxybutyrylation is reno-protective

2024-12-21

Abstract excerpt

Starvation, intermittent fasting and exercise, all of which are recommended lifestyle modifiers share a common metabolic signature, ketogenesis to generate the ketone bodies, predominantly β-hydroxybutyrate. β-hydroxybutyrate exerts beneficial effects across various contexts, preventing or mitigating disease. We hypothesized that these dynamic health benefits of β-hydroxybutyrate might stem from its ability to reg...

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Literature Corpus work: b982a571-c301-57e7-bbe0-152c7cfa1e73
DOI: 10.1101/2024.12.18.628574

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